Janus Kinase Inhibitors in Dermatology
نویسندگان
چکیده
منابع مشابه
Advances in the Inhibitors of Janus Kinase
In recent years, for the lesion site, studies at the molecular level of drugs targeting protein molecules has been a major research method for exploiting new, high-efficiency drugs with low toxicity [1]. Janus kinases (JAKs) are important signal transducers of many cytokines, growth factors and interferon. In recent years, it has been found in cancer cells and cells transfected with oncogenes t...
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Alopecia areata (AA) is an autoimmune disease due to T cell attack of observation made in a special patient is complemented with mechanisthe hair follicles and breakdown of their immune privilege resulting in transient non-scarring hair loss which may last from weeks to decades and which presents an enormous psychological burden. As so far no FDA approved successful treatments for AA are availa...
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Inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, are disabling conditions characterised by chronic, relapsing inflammation of the gastrointestinal tract. Current treatments are not universally effective or, in the case of therapeutic antibodies, are hampered by immune responses. Janus kinase inhibitors are orally delivered small molecules that target cytokine signall...
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ژورنال
عنوان ژورنال: Indian Journal of Drugs in Dermatology
سال: 2019
ISSN: 2455-3972
DOI: 10.4103/ijdd.ijdd_38_18